cowpox virus การใช้

• The cowpox virus can infect humans, though the resulting disease is usually relatively mild.
• It was vaccines made from the cowpox virus that eliminated smallpox from the globe.
• Smallpox vaccine is actually live vaccinia, or cowpox virus, and is not an attenuated virus.
• Although Jenner had used cowpox virus, a third virus, vaccinia, became the standard vaccine against smallpox.
• He is studying the pill in mice infected with the cowpox virus, which is closely related to smallpox.
• The cowpox virus contains 186 thousand base pairs of DNA, which contains the information for about 187 genes.
• Experts say vaccinia is related to the smallpox and cowpox viruses, but its origin is a major scientific mystery.
• Some viruses express caspase inhibitors that inhibit caspase activity and an example is the CrmA protein of cowpox viruses.
• Cowpox virus is harmless but the smallpox virus, though closely related, is one of the most devastating viruses known.
• The boy, James Phipps ( 1788 1853 ), survived the experimental inoculation with cowpox virus and suffered only a mild fever.
• Within the Othopoxvirus genus Cowpox virus strain Brighton Red, Ectromelia virus and Monkeypox virus do not group closely with any other member.
• Buller said colleagues at the Army's biodefense institute at Fort Detrick, Md ., were planning to test the superlethal cowpox virus on mice.
• They altered the DNA of cowpox virus by inserting a gene from other viruses ( namely Herpes simplex virus, hepatitis B and influenza ).
• Scientists have not determined exactly when the change or mutation occurred, but the effects of vaccinia and cowpox virus as vaccine are nearly the same.
• The vaccinia virus now used for smallpox vaccination is sufficiently different from the cowpox virus found in the wild as to be considered a separate virus.
• Rose noted that there was a precedent for using live viruses as a therapy : the vaccinia cowpox virus that was used to vaccinate people against smallpox.
• In 1939 Allan Watt Downie showed that the smallpox vaccines being used in the 20th century and cowpox virus were not the same, but were immunologically related.
• In 1796, the discovery of vaccination the use of the related cowpox virus to immunize against smallpox by Edward Jenner revolutionized the ability of medicine to deal with smallpox.
• Interest in the prophylactic powers of cowpox virus grew and in May 1796, over 20 years after Jesty had made his inoculations, Edward Jenner began his series of vaccination experiments.
• Smallpox was the first disease to be widely prevented by vaccination due to pioneering work by the English physician and scientist Edward Jenner in the eighteenth century using cowpox virus.